Best Western Santa Fe
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Best Western Santa Fe

Hotel
4600 I-40, Amarillo, TX 79103, USA
(800) 774-2348 · Ext 12856, then #
www.bestwestern.com/en_US/book/hotel-rooms.44418.html?iata=00171880&ssob=BLBWI0004G&cid=BLBWI0004G:google:gmb:44418

Nestled right on the iconic Route 66 in Amarillo, the Best Western Santa Fe offers a unique blend of classic charm and modern comfort, perfect for weary travelers exploring the Mother Road. With its vibrant Southwestern decor and hospitable atmosphere, you’ll feel at home while soaking in a piece of Americana history. Enjoy spacious rooms, a refreshing pool, and quick access to local attractions, making this hotel a must-stop for Route 66 adventurers seeking both relaxation and adventure. Experience the spirit of the road in style!

Top Reviews
John Collier

John Collier

a month ago

"We arrived just after 9pm after a very long day of driving. Ashly, the front desk clerk was very friendly and patient. The process was simple and seamless. The lobby was clean and inviting, the room was just as clean. We highly recommend this hotel and would absolutely stay again when in the area!"

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mehul patel

mehul patel

2 months ago

"Rooms were clean. The location was also good and felt safe. There is plenty of parking available. The staff was welcoming and helpful. Seems like this is new hotel or recently renovated. it's close to downtown. Also, while we did not eat, the breakfast looked good."

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Bill Ferrel

Bill Ferrel

4 months ago

"Nice new hotel and an ok location. Service was outstanding, room with clean, comfortable, and mostly quiet. I'd call it a good value! Breakfast was pretty typical for a "hot" breakfast. So nothing special, but quality was decent and what we expected. We would stay here again! And overall recommend it."

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Bradley Patterson

Bradley Patterson

3 months ago

"I had the most amazing experience here. I have no complaints whatsoever. Customer service was excellent, rooms were exceptionally clean, breakfast was great, and as a truck driver I appreciated the spacious and secured parking they provided in the back of the hotel. I would definitely recommend this BW to others and would return again."

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Best Western Santa Fe | Route 66 Hotel in Amarillo, Texas