Comfort Inn & Suites Saint Louis Lafayette Square

Nestled along the historic Route 66 in the vibrant Lafayette Square, the Comfort Inn & Suites offers a unique blend of modern comfort and vintage charm for the quintessential American road trip experience. With easy access to iconic attractions and local eateries, this hotel is a perfect launching point for exploring St. Louis's rich history and culture. After a day on the Mother Road, unwind in spacious rooms that promise a restful stay, making it an ideal stop for Route 66 travelers eager to soak in the essence of the journey.