Dos Hermanas Compound
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Dos Hermanas Compound

Hotel
443 W San Francisco St, Santa Fe, NM 87501, USA
(800) 774-2348 · Ext 14159, then #
doshermanascompound.com

Nestled along the iconic Route 66 in Santa Fe, Dos Hermanas Compound invites travelers to step into a vibrant blend of history and Southwestern charm. With its richly adorned adobe-style architecture and lush gardens, this unique hotel captures the spirit of the Mother Road, offering guests a serene escape just moments from the bustling city. Each room tells a story, infused with local art and culture, ensuring an unforgettable stay that honors the journey of countless adventurers along this legendary highway.

Opening Hours
MondayOpen 24 hours
TuesdayOpen 24 hours
WednesdayOpen 24 hours
ThursdayOpen 24 hours
FridayOpen 24 hours
SaturdayOpen 24 hours
SundayOpen 24 hours
Top Reviews
Clarissa Costa

Clarissa Costa

5 months ago

"Fantastic stay, dog-friendly and perfectly located! I chose this hotel mainly for its location and the fact that they welcome dogs, and I couldn’t have been happier with the experience! Everything worked smoothly: the bed was super comfortable, the towels were clean and soft, and the small kitchen had everything we needed (though we did miss having wine glasses!). The location is absolutely amazing. We were able to explore the entire Santa Fe Plaza and downtown area on foot, which made our stay even more enjoyable."

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Fran N

Fran N

2 months ago

"Great place to stay. This was our second time staying here. Super close to the square, rail yard and all of the other sites. Super charming, easy to get to and away from the crowds. Will stay here again on our next visit to the area."

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Chantelle Kreutter

Chantelle Kreutter

11 months ago

"We had a great stay in Casita #5. Unit is as pictured, incredible location, safe gated parking, clean and comfy, communicative host. My favorite part was the private patio for afternoon snacks and sun. Our pugs loved sitting out there with us. We hope to return with friends and book a few units out! Thank you Mo!"

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Kevin Halliburton

Kevin Halliburton

8 months ago

"Second stay at Dos Hermanas and we're definitely coming back again the next time we're in town. Quiet, private and secure with convenient parking. I've stayed in 2 different casitas and both were clean and comfortable with all the essentials you need if you have a lazy morning or an early evening but the location is amazing so if you're like me, you won't actually spend much time in the casita with the Square and the Railyard and all the dining, shops and galleries you could ask for a short, easy walk away. The management communicate effectively and are attentive but not intrusive. Perfect stay!"

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Laszlo Kovacs

Laszlo Kovacs

10 months ago

"Casita 3 is a clean and comfortable apartment with a fully equipped kitchen. It is easily approachable by car and walking distance from the Plaza. Dos Hermanas provides a safe, enclosed and gated parking site right next to the casitas within its courtyard. Hassle-free self-check-in and check-out and regular email communication from management. We will definitely stay here again when we return to Santa Fe."

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Dos Hermanas Compound | Route 66 Hotel in Santa Fe, New Mexico