The Merry House Inn

1 / 10

The Merry House Inn

Hotel

125 Defiance Rd, Defiance, MO 63341

YouTube Tutorial

Your ultimate companion for planning the perfect Route 66 road trip. Discover iconic stops, hidden gems, and unforgettable experiences along the Mother Road.

Explore

Plan a Trip
Maps
Iconic 66
Historic Route 66
Visitor Centers
Events
Hotels
Restaurants
Shops
Experiences
Deals

Information

Browse by State
Road Trips
Travel Tips
Quick Guide
History of Route 66

Account

Login
Sign Up

Company

About
Partner With Us

© 2026 Drive Route 66. All rights reserved.

Privacy PolicyTerms of ServiceCookie PolicyConsent Preferences

The Merry House Inn | Route 66 Hotel