Clayton Chamber of Commerce

Nestled along the iconic Route 66, the Clayton Chamber of Commerce Visitor Center is a gateway to the heart of St. Louis and its vibrant history. Here, Route 66 travelers can find a treasure trove of local insights, unique attractions, and wonderful hospitality. With engaging exhibits and friendly staff, this charming center is the perfect pit stop to discover hidden gems and plan your next adventure along the Mother Road. Don’t miss out on experiencing the rich culture and eclectic spirit that make this area a must-see on your journey!